The National Heart, Lung, and Blood Institute (NHLBI) recommended dosing for systemic prednisone, prednisolone, or methylprednisolone in pediatric patients whose asthma is uncontrolled by inhaled corticosteroids and long-acting bronchodilators is 1–2 mg/kg/day in single or divided doses. It is further recommended that short course, or "burst" therapy, be continued until the patient achieves a peak expiratory flow rate of 80% of his or her personal best or until symptoms resolve. This usually requires 3 to 10 days of treatment, although it can take longer. There is no evidence that tapering the dose after improvement will prevent a relapse.
WWE canceled the scheduled three-hour-long live Raw show on June 25 (which, coincidentally, was supposed to be a memorial for the Mr. McMahon character), and replaced the broadcast version with a tribute to his life and career, featuring past matches, segments from the Hard Knocks: The Chris Benoit Story DVD , and comments from wrestlers and announcers from the Raw , SmackDown! , and ECW brands. Shortly after the program aired, many of the aired comments were posted on . It was not until the program was nearly over that reports surfaced that police were working under the belief that Benoit murdered his wife and son before killing himself.
In placebo-controlled trials in rheumatologic indications, approximately 37% of patients treated with Enbrel developed injection site reactions. In controlled trials in patients with PsO, 15% of adult patients and 7% of pediatric patients treated with Enbrel developed injection site reactions during the first 3 months of treatment. All injection site reactions were described as mild to moderate (erythema, itching, pain, swelling, bleeding, bruising) and generally did not necessitate drug discontinuation. Injection site reactions generally occurred in the first month and subsequently decreased in frequency. The mean duration of injection site reactions was 3 to 5 days. Seven percent of patients experienced redness at a previous injection site when subsequent injections were given.