Some of the approved drugs are synthetic versions of the natural hormones, such as trenbolone acetate and zeranol. Just like the natural hormone implants, before FDA approved these drugs, FDA required information and/or toxicological testing in laboratory animals to determine safe levels in the animal products that we eat (edible tissues). Furthermore, FDA required that the manufacturers demonstrate that the amount of hormone left in each edible tissue after treatment is below the appropriate safe level. As described above, a safe level is a level which would be expected to have no harmful effect in humans.
Ann N Y Acad Sci 1990;587:371-5.
Cytokines and osteoporosis. Fujita T, Matsui T, Nakao Y, Shiozawa S,
Imai Y. Conditions associated with immune dysfunction such as aging,
corticosteroid therapy, and rheumatoid arthritis are associated with
osteoporosis, which is also more common in females than in males, like
most of the autoimmune-collagen diseases. Peripheral lymphocyte subsets
CD4/CD8 were higher in patients with senile osteoporosis than in the
age-matched controls, and returned to normal after 1 month of 1 alpha(OH)vitamin
D3 treatment. Plasma interferon reflecting macrophage function decreased
with advance in age and increased in response to 1 alpha(OH)D3 treatment.
As one of the immunoregulators, vitamin D tends to stimulate the macrophage-natural
killer system and suppress the lymphocyte system, stimulating TGF beta
and TNF alpha activity. Senile osteoporosis of low turnover thus appears
to be associated with vitamin D deficiency, low macrophage function,
high CD4 lymphocyte proportion, low IL-1 and high IL-2 activity, low
IFN alpha and high IFN gamma activity, and low TGF beta and TNF alpha
Although both are nutritious, if you want to consume milk as part of your muscle building diet, to meet your protein requirement, choose buffalo's milk over cow's milk. Firstly, buffalo milk is much more easily available than cows milk. Secondly, Buffalo's milk scores slightly better in protein content than cow's milk. While the difference is not huge, but it will certainly add up. A few people would be concerned about the high fat content in buffalo's milk. For this, chose low fat options. If you are only chasing size and looking to increase you calorie intake, choose whole fat. Keep in mind that the fat in milk is majorly saturated which is not a matter of concern. Men require saturated fat to produce testosterone. If your overall saturated fat intake from other sources is not too high, pick whole fat milk. Though taste varies with every individual, generally buffalo's milk is considered to have better taste.