Recettori intracellulari ormoni steroidei

The dorsal root ganglion (DRG) neurons of mammals were known to express a heat-sensitive ion channel that could be activated by capsaicin. [51] The research group of David Julius, therefore, created a cDNA library of genes expressed in dorsal root ganglion neurons, expressed the clones in HEK 293 cells , and looked for cells that respond to capsaicin with calcium influx (which HEK-293 normally not do). After several rounds of screening and dividing the library, a single clone encoding the TRPV1 channel was finally identified in 1997. It was the first TRPV channel to be identified. [5]

Recettori intracellulari ormoni steroidei

recettori intracellulari ormoni steroidei

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recettori intracellulari ormoni steroideirecettori intracellulari ormoni steroideirecettori intracellulari ormoni steroideirecettori intracellulari ormoni steroideirecettori intracellulari ormoni steroidei

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