Help I have a friend who is a gym goer Im not sure of his quantity or how long he has been taking steroids, but stopped recently because he had really bad neck pain. No dr or scan, ultrasound etc showed anything. Put on huge pain killer amounts didnt help alot but felt after about six weeks some relief. Until today when he thinks a prior knee issue has flared up. If this a result of steroid abuse how long before it heals? Im pretty sure he wont touch them again. He can handle all over aches and pains but these last two injuries have had him off work.
The black box warning on the . FDA-approved ciprofloxacin label warns of an increased risk of tendinitis and tendon rupture, especially in people who are older than 60 years, people who also use corticosteroids, and people with kidney, lung, or heart transplants. Tendon rupture can occur during therapy or even months after discontinuation of the medication.  A case-control study  performed using a UK medical care database found that fluoroquinolone use was associated with a -fold increase in tendon problems. The relative risk increased to in those over 60 years of age and to in those over the age of 60 who were also taking corticosteroids. Among the 46,766 quinolone users in the study, 38 (%) cases of Achilles tendon rupture were identified. A study performed using an Italian healthcare database reached qualitatively similar conclusions. 
July 3, 2000 - The FDA has approved a new blood thinner to prevent and treat abnormal blood clotting related to heparin use. The drug is argatroban (Novastan), developed by Texas Biotech. It blocks thrombin, a key factor in blood clotting.
Heparin is given to more than 12 million people a year to prevent blood clots. As many as 360,000 of these patients develop abnormal blood clotting, known as HIT (heparin-induced thrombocytopenia). About 120,000 of these patients develop a serious complication from HIT, such as stroke or limb amputation. Up to 36,000 patients a year die from complications.
HIT usually happens 5 to 10 days after heparin treatment. Diagnosis can be difficult and is made tougher because doctors expect bleeding - not clotting - with this kind of condition. So doctors sometimes worsen the condition by continuing blood thinner therapy. Argatroban is the first direct thrombin inhibitor approved to prevent and treat abnormal clotting in HIT patients.
Argatroban's safety and effectiveness were shown in 2 clinical trials of 568 patients getting the drug versus 193 untreated "controls." All were diagnosed with HIT. Argatroban improved outcomes for the HIT patients. In trials with patients monitored for over a month, 34% of argatroban patients suffered death, amputation or new clot compared to 43% of controls.
Source: Reuters Health